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Dr Tyna Moore
My post https://www.facebook.com/greg.schipper/videos/1795033607707934/? .
The Dangers Of Ibuprofen…Your Kidneys, Bones, Heart, Tendons & Gut Are All Being Harmed By NSAIDs.
NSAIDs cause systemic issues affecting the kidneys, gut microbiome, stomach & cardiovascular health.
"NSAIDs Cut Off The Crucial Healing Process That Is Required To Heal Injuries Of Soft Tissue, Tendons & Bone."
It takes 300 days for full restorative collagen production & stability. The entire healing cascade must come to fruition without interruption in order to lay down healthy strong, stable collagen.
If you cut off that process for the first 2 weeks by taking Ibuprofen or any NSAID, you are shooting yourself in the foot. It has been known since the 90s that collagen does not regenerate when NSAIDs are taken post injury.
NSAIDs inhibit bone healing & should never be taken if you have a fracture of any kind, even a stress fracture.
The Harms Of NSAIDs Reside In Its Mode Of Action That Inhibits COX-1 & COX-2 Enzymes:
Kidney Dysfunction: COX Enzymes blocked by taking NSAIDs, causes acute renal damage by reducing Prostaglandin production which reduces blood flow to the kidneys. This leads to acute kidney injury (AKI), chronic kidney disease (CKD), edema, hypertension, hyperkalemia & nephrotic syndrome.
Cardiovascular Harm: Chronic COX-2 inhibition skews the balance between thromboxane & prostacyclin, elevating clotting risks & arterial stiffness.
Gut Permeability: On a systemic level, NSAID use compromises the gut barrier by reducing protective mucosal prostaglandins, increasing intestinal permeability & triggering inflammation. NSAIDs eliminate the delicate endothelial barrier, resulting in ulcers, gut permeability & IBD Inflammatory Bowel Diseases.
Bone Rebuilding Post Fracture: NSAIDs disrupt osteoblast & osteoclast function, weakening bone healing & regeneration. This prevents fractured bone from healing fully & results in bone pain & increased risk for future fractures.
Collagen Production: By blocking COX-2, NSAIDs reduces growth factor-beta (TGF-β) & other signaling molecules necessary for fibroblast activity, blocking Type I collagen—a critical component for tendon and ligament repair.

NSAID Acute & Chronic Kidney Injury
https://www.sciencedirect.com/science/articl?fbclid=IwY2xjawKN1jNleHRuA2FlbQIxMABicmlkETFhb1pVYlpSOTFIVk45YnY2AR5S3AH08ipbkHaLbw-Qrn5fKE_1tR2Skbo4iyM8FGa3ejJVvhkKUhHvepMZsQ_aem_ManE5Cn_iYNC_pnm8X16yQ
https://www.sciencedirect.com/science/article/abs/pii/S0953620522001728?fbclid=IwY2xjawKN2YZleHRuA2FlbQIxMABicmlkETFwM3RDdkZDQ0tpS0xodDRuAR7v3fFGkklDzVKVB4rNAp6nPLQ-JkK1IyQ_qg0AVwGCMA0QJHhJ81WgMA-_Ww_aem_oFrbN2ED8W2Tkeh8E2-m9A .

Gastrointestinal Permeability From NSAID Use

https://pubmed.ncbi.nlm.nih.gov/19148789/#:~:text=Results:%20Virtually%20all%20studies%20agree,and%20severity%20of%20NSAID%20enteropathy. .

Bone Fracture Non Healing From NSAID Use

https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2024.1428240/full .
Podcast: @MarkSmellyBell